Endocrine Abstracts

Clinically non-functioning pituitary adenomas account for about one-third of pituitary tumors. The majority of them are pathologically classified as gonadotropinomas or null-cell adenomas without hormonal expression. The rest represent silent corticotroph adenomas and plurihormonal tumors. Conservative therapy with dopamine agonists and somatostatine analogues is effective in some cases only depending on the expression of somatostatine (SSTR) and dopamine 2 receptors (D2R).</p...